Journal article
Embracing the era of antimicrobial peptides with marine organisms
P Chen, T Ye, C Li, P Praveen, Z Hu, W Li, C Shang
Natural product reports (Print) | Royal Society of Chemistry | Published : 2024
DOI: 10.1039/d3np00031a
Abstract
Covering: 2018 to Jun of 2023 The efficiency of traditional antibiotics has been undermined by the proliferation of antibiotic-resistant pathogenic microorganisms, necessitating the pursuit of innovative therapeutic agents. Antimicrobial peptides (AMPs), which are part of host defence peptides found ubiquitously in nature, exhibiting a wide range of activity towards bacteria, fungi, and viruses, offer a highly promising candidate solution. The efficacy of AMPs can frequently be augmented via alterations to their amino acid sequences or structural adjustments. Given the vast reservoir of marine life forms and their distinctive ecosystems, marine AMPs stand as a burgeoning focal point in the q..
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Grants
Awarded by National Key Research and Development Program of China
Funding Acknowledgements
This work was financially supported by the National Key R&D Program of China (2018YFA0902500), the National Natural Science Foundation of China (41706137), CAS Key Laboratory of Science and Technology on Operational Oceanography (No. OOST2021-07). W. L. is the recipient of NHMRC Investigator Grant EL1 (APP2018256) and veski Victoria Fellowship.